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The drug is excreted mainly during the urine, largely as inactive metabolites and small amounts of no cost and conjugated morphine. Negligible amounts of codeine and its metabolites are located in the feces.A likely lethal symptom advanced in some cases generally known as Neuroleptic Malignant Syndrome (NMS) has actually been reported in associatio

Codeine: Narcotic analgesics, which include codeine, exert their primary results to the central nervous process and gastrointestinal tract. The analgesic consequences of codeine are due to its central motion; nonetheless, the exact web-sites of motion haven't been decided, and also the mechanisms concerned seem like very intricate.Hyperexcitability